Modulation in vitro of H-ras oncogene expression by trans-splicing
نویسندگان
چکیده
منابع مشابه
H-Ras Oncogene Expression and Angiogenesis in Experimental Liver Cirrhosis
Background. Proto-oncogenes, particularly ras, may not only affect cell proliferation but also contribute to angiogenesis by influencing both proangiogenic and antiangiogenic mediators. The aim of this study was to investigate whether any relationship exists between ras expression and angiogenesis during diethylnitrosamine- (DEN-) induced experimental liver fibrosis. Materials and Methods. Live...
متن کاملMelatonin induces antiproliferative activity through modulation of apoptotic pathway in H-ras oncogene transformed 5RP7 cells
* Correspondence: [email protected]
متن کاملIn vitro trans-splicing in Saccharomyces cerevisiae.
The interactions established at the 5'-splice site during spliceosome assembly are likely to be important for both precise recognition of the upstream intron boundary and for positioning this site in the active center of the spliceosome. Definition of the RNA-RNA and the RNA-protein interactions at the 5' splice site would be facilitated by the use of a small substrate amenable to modification ...
متن کاملAntipain-induced suppression of oncogene expression in H-ras-transformed NIH3T3 cells.
Antipain (AP; 50 micrograms/ml) inhibits transformation of NIH3T3 cells after transfection with an activated H-ras oncogene. To determine whether AP effects on transformation are associated with alterations in oncogene expression, NIH3T3 cells were cotransfected with an activated H-ras oncogene and the selectable marker gene aph, and gene expression was quantified. Fifty percent of geneticin-re...
متن کاملAntipain-induced Suppression of Oncogene Expression in H-ras-transformed NIH3T3 Cells1
Antipain (AP; 50 Mg/ml) inhibits transformation of NIH3T3 cells after transfection with an activated H-ras oncogene. To determine whether AP effects on transformation are associated with alterations in oncogene expression, NIH3T3 cells were cotransfected with an activated H-ras oncogene and the selectable marker gene uph. and gene expression was quantified. Fifty percent of geneticin-resistant ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Oncogene
سال: 2001
ISSN: 0950-9232,1476-5594
DOI: 10.1038/sj.onc.1204473